Marta Magariños has a PhD in Science from the Universidad Autónoma de Madrid. The studies carried out during her doctoral thesis and the first post-doctoral years focused on the study of LIM-HD proteins in determining the early neuronal identity of Drosophila melanogaster. She has done several international research stays for approximately two years at the Institute of Biology III (Freiburg, Germany), the Neurobiotechnology Center (Columbus, USA), the Baylor College of Medicine (Houston, USA) and the Institute for Medical Radiation Science and Cell Research the University of Würzburg, MSZ (Würzburg, Germany).
From 2005 to 2019 her research was focused on chicken and mouse models, studying the molecular and cellular bases that drive inner ear development and function within the group led by Dra. Isabel Varela-Nieto (Alberto Sols Institute of Biomedical Research (CSIC-UAM). She studied the factors (IGF-1, TGF-b2) and the signaling pathways (RAF-MEK-ERK, PI3K-AKT, TGFb/SMAD) through which the different cellular actions are carried out. She has studied the specification of the acoustic-vestibular ganglion during early neurogenesis, the relationships between the survival and cell death pathways, autophagy, proliferation, and early cell differentiation.
Marta Magariños is currently an Associated Professor of Fisiología Animal in the Biology Department of the UAM where she is studying the role of physiological cell senescence during development. For this, the most pertinent models are used in each case, whether they are vertebrates (chicken embryos and mice) or invertebrates (Drosophila melanogaster). Currently, the group has two Doctoral Theses in progress (Pablo Palau Irisarri and Félix-Sánchez Valverde) centered on the role of senescence during CHARGE syndrome and on cell senescence upon nervous system damage in Drosophila melanogaster.